Characterization of sulfur mustard resistant keratinocyte cell line HaCaT/SM
M Wolf, M Siegert, S Rothmiller, N Scheithauer… - Toxicology letters, 2016 - Elsevier
Abstract Background The cell line HaCaT/SM was derived from the human keratinocyte cell
line HaCaT. HaCaT/SM cells display a high resistance against sulfur mustard (SM). Intention
of the presented study was to determine the cellular and molecular differences between
HaCaT/SM and HaCaT so as to evaluate which changes might be responsible for being
resistant against SM. Methods Both cell lines HaCaT and HaCaT/SM were analyzed with
respect to their cell growth, nuclei perimeter, clonogenicity and secretion profile. Moreover …
line HaCaT. HaCaT/SM cells display a high resistance against sulfur mustard (SM). Intention
of the presented study was to determine the cellular and molecular differences between
HaCaT/SM and HaCaT so as to evaluate which changes might be responsible for being
resistant against SM. Methods Both cell lines HaCaT and HaCaT/SM were analyzed with
respect to their cell growth, nuclei perimeter, clonogenicity and secretion profile. Moreover …
