Disseminated intravascular coagulation (DIC) is a heterogeneous group of disorders, which
manifest as a spectrum of haemorrhage and thrombosis complicating many primary
conditions including sepsis, trauma and malignancies. The pathophysiology of this condition
is complex. In the recent years there is growing evidence that damage associated molecular
patterns (DAMPs) play a crucial role in the pathogenesis of DIC. Upon cell-death and/or cell
activation of hematopoietic and parenchymal cells extracellular cell-free DNA as well as …