Bacterial meningitis is still an important infectious disease causing death and disability.
Invasive bacterial infections of the CNS generate some of the most powerful inflammatory
responses known in medicine. Although the components of bacterial cell surfaces are now
chemically defined in exquisite detail and the interaction with several receptor pathways has
been discovered, it is only very recently that studies combining these advanced biochemical
and cell biological tools have been done. Additional to the immunological response direct …