[PDF][PDF] Severe mycobacterial IRIS in advanced HIV has features of hemophagocytic lymphohistiocytosis and requires prolonged immune suppression
JM Rocco, E Laidlaw, F Galindo - Clin Infect Dis, 2022 - scholar.archive.org
1 2 Background: People with HIV and mycobacterial infections can develop immune
reconstitution 3 inflammatory syndrome (IRIS) after starting antiretroviral therapy. Severe
mycobacterial-IRIS 4 has an overlapping clinical phenotype with hemophagocytic
lymphohistiocytosis (HLH). 5 Objective: To evaluate the pathophysiologic similarities
between mycobacterial-IRIS and HLH 6 and identify clinical and immune predictors of
mycobacterial-IRIS severity. 7 Methods: HLH-criteria were applied to a longitudinal cohort of …
reconstitution 3 inflammatory syndrome (IRIS) after starting antiretroviral therapy. Severe
mycobacterial-IRIS 4 has an overlapping clinical phenotype with hemophagocytic
lymphohistiocytosis (HLH). 5 Objective: To evaluate the pathophysiologic similarities
between mycobacterial-IRIS and HLH 6 and identify clinical and immune predictors of
mycobacterial-IRIS severity. 7 Methods: HLH-criteria were applied to a longitudinal cohort of …
Severe mycobacterial immune reconstitution inflammatory syndrome (IRIS) in advanced human immunodeficiency virus (HIV) has features of hemophagocytic …
JM Rocco, E Laidlaw, F Galindo… - Clinical Infectious …, 2023 - academic.oup.com
Background People with HIV and mycobacterial infections can develop immune
reconstitution inflammatory syndrome (IRIS) after starting antiretroviral therapy (ART).
Severe mycobacterial IRIS has an overlapping clinical phenotype with hemophagocytic
lymphohistiocytosis (HLH). We evaluated the pathophysiologic similarities between
mycobacterial IRIS and HLH to identify clinical and immune predictors of mycobacterial IRIS
severity. Methods HLH criteria were applied to a longitudinal cohort of 80 patients with HIV …
reconstitution inflammatory syndrome (IRIS) after starting antiretroviral therapy (ART).
Severe mycobacterial IRIS has an overlapping clinical phenotype with hemophagocytic
lymphohistiocytosis (HLH). We evaluated the pathophysiologic similarities between
mycobacterial IRIS and HLH to identify clinical and immune predictors of mycobacterial IRIS
severity. Methods HLH criteria were applied to a longitudinal cohort of 80 patients with HIV …
